|
KMID : 1100920180390050295
|
|
Korean Journal of Family Medicine
2018 Volume.39 No. 5 p.295 ~ p.299
|
|
|
Association between Serum Uric Acid and Oxidative Stress in Korean Adults
|
|
Ok Eun-Jeong
Kim Ki-Young
Park Sat-Byul
|
|
|
Abstract
|
|
|
Background: Oxidative stress is implicated in the pathogenesis and development of lifestyle-related diseases. In the present study, we evaluated the correlation between the serum uric acid (UA) levels and oxidative status in Korean adults.
Methods: The subjects were 5,093 individuals (2,041 women and 3,052 men) who underwent a health checkup between June 2012 and December 2016. Oxidative stress levels (derivatives of reactive oxygen metabolites [d-ROMs]) and antioxidant potential (biological antioxidant potential [BAP]) were measured. Metabolic markers, including UA, were also examined.
Results: Higher serum UA levels were associated with decreased levels of d-ROMs (P<0.05). The UA levels were positively associated with BAP levels (P<0.001).
Conclusion: Serum UA is related to oxidative status, especially antioxidant capacity, in Korean adults; UA may play a role in antioxidant defense systems in humans.
|
|
|
KEYWORD
|
|
|
Uric Acid, Oxidative Stress, Reactive Oxygen Species, Antioxidants
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|